warnings

What is the most important information I should know about Deucravacitinib (Oral)?

You should not use deucravacitinib if you are allergic to it.

Tell your doctor if you have ever had:

liver or kidney disease;
hepatitis B or C;
high blood levels of fat (triglycerides);
any type of cancer;
tuberculosis or have been exposed to tuberculosis;
if you have an infection that keeps returning or does not go away;
if you are being treated for an infection;
if you have recently received or are scheduled to receive a vaccine; or
if you have high blood pressure, high cholesterol, diabetes, menopause (women), family history of coronary artery disease, being overweight, or being over 50, or if you smoke.

Tell your doctor if you are pregnant or breastfeeding.

Side Effects

What are the side effects of Deucravacitinib (Oral)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Deucravacitinib can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.

Also call your doctor at once if you have:

signs of infection--fever, chills, muscle pain, shortness of breath, weight loss, diarrhea or stomach pain, burning when you urinate, feeling very tired, skin warmth or redness, painful skin sores, or coughing up blood.

Common side effects may include:

cold symptoms such as stuffy nose, sneezing, sore throat;
cold sores, sores on your gums, tongue or mouth;
folliculitis (redness or crusting around your hair follicles); or
acne.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Dosage Guidelines & Tips

How to take Deucravacitinib (Oral)?

Use Deucravacitinib (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take deucravacitinib once every day, with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

You will need medical tests before you start taking deucravacitinib and while taking this medicine.

Store at room temperature away from moisture and heat.

What should I do if I missed a dose of Deucravacitinib (Oral)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.